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Sema4.ai alternatives · AI Agents

Open-source alternatives to Sema4.ai

Sema4.ai is not described as open source on its own site. 23 of the 101 other AI agents in this directory are open source, according to their own sites.

Sema4.ai's current pricing could not be confirmed from its own site. 21 of them are free or have a free plan.

23 tools · Listings checked up to Nov 12, 2026 · Where the facts come from

The 12 closest to Sema4.ai

  1. AutoGPT

    Open-source agent platform with a hosted team of AI Experts

    • AutoGPT has a free plan. Sema4.ai does not.
    • AutoGPT is open source, according to its own site.
  2. Dify

    Open-source platform for building AI agents and agentic workflows

    • Dify has a free plan. Sema4.ai does not.
    • Dify is open source, according to its own site.
    • Dify also covers no-code.
  3. Kortix

    Open-source platform for running AI agents from a git repo you own

    • Kortix has a free plan. Sema4.ai does not.
    • Only Kortix lists macOS, Windows, Linux, iOS and Android apps.
    • Kortix is open source, according to its own site.
  4. Sim

    Open-source workspace for building and running AI agents

    • Sim has a free plan. Sema4.ai does not.
    • Only Sim lists a macOS app.
    • Sim is open source, according to its own site.
  5. Agenta

    Open-source workspace for building team AI agents and automations

    • Agenta has a free plan. Sema4.ai does not.
    • Agenta is open source, according to its own site.
    • Agenta also covers templates and no-code.
  6. Letta

    Stateful agents with long-term memory, from the MemGPT team

    • Letta has a free plan. Sema4.ai does not.
    • Letta is open source, according to its own site.
    • Sema4.ai is self-hostable, according to its own site.
  7. Mastra

    TypeScript framework for building and running AI agents

    • Mastra has a free plan. Sema4.ai does not.
    • Mastra is open source, according to its own site.
  8. Mem0

    Memory layer that lets AI agents remember across sessions

    • Mem0 has a free plan. Sema4.ai does not.
    • Mem0 is open source, according to its own site.
    • Sema4.ai also covers workflow automation.
  9. OpenClaw

    Open-source personal AI agent you run yourself and message in chat

    • OpenClaw has a free plan. Sema4.ai does not.
    • Only OpenClaw lists macOS, Windows, Linux, iOS and Android apps.
    • OpenClaw is open source, according to its own site.
    • OpenClaw also covers chat assistant.
  10. Hermes Agent

    Open-source AI agent with persistent memory and a messaging gateway

    • Hermes Agent has a free plan. Sema4.ai does not.
    • Only Hermes Agent lists macOS, Windows and Linux apps.
    • Hermes Agent is open source, according to its own site.
    • Hermes Agent also covers chat assistant.
  11. NanoClaw

    Open-source personal AI agent that runs in containers you host

    • NanoClaw has a free plan. Sema4.ai does not.
    • Only NanoClaw lists macOS, Linux and Windows apps.
    • Only Sema4.ai lists a web app.
    • NanoClaw is open source, according to its own site.
  12. Eigent

    Open-source desktop app for working alongside AI agents

    • Eigent has a free plan. Sema4.ai does not.
    • Only Eigent lists macOS, Windows and Linux apps.
    • Only Sema4.ai lists a web app.
    • Eigent is open source, according to its own site.

Common questions

Is there an open-source alternative to Sema4.ai?

Yes. AutoGPT, Dify, Kortix, Sim, Agenta, Letta, Mastra, Mem0 and 15 more are open source, according to their own sites.

Is Sema4.ai open source?

Sema4.ai is not described as open source on its own site. The listing was checked on Nov 12, 2026 against the pages it cites.

Which of these AI agents are free?

AutoGPT, Dify, Kortix, Sim, Agenta, Letta, Mastra, Mem0 and 13 more are free or have a free plan.

When was this checked?

Each listing shows its own date. On this page they run from Oct 5, 2026 to Nov 12, 2026. Vendors change prices and plans without notice, so confirm on their site before you buy.

This page is built from the listings. A tool is here because its listing says so, and the order is how close each is to Sema4.ai: the alternatives its listing names first, then the tools that share the most features with it.